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Author Panan Ratthawongjirakul
Alternative Author Vorraruthai Thongkerd
Songklanakarin Journal of Science and Technology
TitleFresh garlic extract inhibits Staphylococcus aureus biofilm formation under chemopreventive and chemotherapeutic conditions
ImprintVol. 38 No. 4, July-August 2016
Call# FOOD 7774

CALL # Volume Number Month Year Barcode Status

AbstractStaphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) are the leading aetiological pathogens of nosocomial infections worldwide. These bacteria form biofilms on both biotic and abioti c surfaces causing biofilm-associated infections. Within the biofilm, these bacteria might develop persistent and antimicrobial resistant character- istics resulting in chronic infections and treatment failures. Garlic exhibits broad pharmaceutical properties and inhibitory activities against S. aureus . We investigated the effects of aqueous fresh garlic extract on biofilm formation in S. aureus ATCC25923 and MRSA strains under chemopreventive and chemotherapeutic conditions. The viable bacteria and biof ilm levels were quantified through colony count and crystal violet staining, respectively. The use of fr esh garlic extract under both conditions significantly inhibited biofilm formation in S. aureus strains ATCC25923 and MRSA. Garlic could be developed as either a prophylactic or therapeutic agent to manage S. aureus biofilm-associated infections.
DescriptPage 381-389
Subject fresh garlic extrac
biofilms
MRSA
Staphylococcus aureus
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