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Author Ting-chi Wen
Alternative Author Chao Kang
Ji-chuan Kang
Guang-rong Li
Kevin D. Hyde
Chiang Mai Journal of Science
TitleOptimization of Solid-state Fermentation for Fruiting Body Growth and Cordycepin Production by Cordyceps militaris
ImprintVol. 41 No. 4 , September 2014
Call# FOOD 7829

CALL # Volume Number Month Year Barcode Status

AbstractCordyceps sinensis has traditionally been used in Traditional Chinese Medicine, however C. militaris has gained importance and is also used as a functional food. Cordyceps militaris contains similar biochemical components as C. sinensis as well as the anti-cancer component cordycepin. Because C. militaris can be grown in culture and has significant medicinal affects, market demand for artificial C. militaris has increased. This study was aimed to optimize the conditions of solid-state fermentation for fruiting body growth and cordycepin production from C. militaris by one-factor-at-a-time and orthogonal layout methods. The optimal culture substrate was brown rice. The optimal fruiting body growth and cordycepin production were observed at relatively low pH value. The optimum composition were 40 g/L glucose, 5 g/L peptone, 1.5 g/L MgSO 4 ? 7H 2 O, 1.5 g/L K 2 HPO 4 and 1.0 mg/L NAA for optimal fruiting body growth and 10 g/L glucose, 10 g/L peptone, 1.0 g/L MgSO 4 ? 7H 2 O, 1.0 g/L K 2 HPO 4 and 1.0 mg/L NAA for cordycepin production. These optimization strategies in solid medium culture lead to a 67.96 % (1.73 ? 0.08 g/bottle) increase in fruiting body yield and a 63.17% (9.17 ? 0.09 mg/g) increase of cordycepin yield in fruiting body, which may be applied in industrial production of cordycepin via solid-state fermentation.
DescriptPage 858-872
Subject C ordyceps militaris
solid-state fermentation