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Author Chalerm Saiin
Alternative Author THE KASETSART JOURNAL NATURAL SCIENCE
TitleIsolation of Anti-malarial Active Compound from Yanang (Tiliacora triandra Diels)
Alternative TitleIsolation of Anti-malarial Active Compound from Yanang (Tiliacora triandra Diels)
ImprintVol.37 No.1, January - March 2003
Call# FOOD 8366

CALL # Volume Number Month Year Barcode Status

AbstractMalaria remains to be one of the serious problems in tropical countries of the increase in antimalarial drug resistance. This investigation was to study the extraction of bioactive compounds with anti-malarial activity from Yanang (Tiliacora triandra Diels) root. The dried root was extracted with chloroform: methanol:ammonium hydroxide mixture (50:50:1). Further isolation and purification of the crude extract using column chromatography and crystallization techniques provided two pure alkaloid compounds: tiliacorinine (I) and tiliacorine (II) with 0.0082 and 0.0029 percent yield, respectively. Structures of I and II were confirmed by spectroscopy techniques and compared with reference data.
DescriptPage 47-51
Subjectanti-malarial
Yanang
Tiliacora triandra Diels
tiliacorinine
tiliacorine
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